The frequency with which you should manually sharpen your knives depends on several factors, including the type of knife, its usage, and the material of the blade. Generally, for home cooks, sharpening should be done every 2-4 months. However, if you use your knives daily, you might need to sharpen them more frequently, perhaps every 1-2 months. 
High-quality knives made from harder steel can hold an edge longer and may require less frequent sharpening compared to knives made from softer steel. Additionally, the type of cutting board you use can affect how often you need to sharpen your knives. Softer materials like wood or plastic are gentler on blades than harder surfaces like glass or stone.
It's also important to distinguish between honing and sharpening. Honing should be done more frequently, ideally before or after each use, to maintain the edge by realigning it. Sharpening, on the other hand, involves removing material to create a new edge and should be done less often.
Pay attention to signs that your knife needs sharpening, such as difficulty cutting through foods, slipping off surfaces, or requiring more force than usual. Regular maintenance, including proper cleaning, storage, and using the right cutting surfaces, can extend the time between sharpenings.
Ultimately, the best guide is your own experience with the knife. If it feels dull or less effective, it’s time to sharpen. Regularly assessing your knives' performance will help you determine the optimal sharpening schedule for your specific needs.