The accuracy of multi-channel handheld temperature meters depends on several factors, including the quality of the sensors, the calibration process, and the environmental conditions in which they are used. Generally, high-quality multi-channel handheld temperature meters can achieve an accuracy of ±0.1°C to ±0.5°C. 
The sensors used in these devices, such as thermocouples, RTDs (Resistance Temperature Detectors), or thermistors, play a crucial role in determining accuracy. RTDs and thermistors typically offer higher accuracy compared to thermocouples, but they may have a more limited temperature range. 
Calibration is another critical factor. Regular calibration against a known standard is necessary to maintain accuracy over time. Manufacturers often provide calibration certificates, and some devices allow for user calibration to ensure ongoing precision.
Environmental conditions, such as ambient temperature, humidity, and electromagnetic interference, can also affect accuracy. Many high-quality meters are designed to minimize these effects, but users should still be aware of potential influences.
The resolution of the device, which is the smallest change it can detect, also impacts perceived accuracy. A device with high resolution can detect smaller changes in temperature, which can be crucial for applications requiring precise measurements.
In summary, while multi-channel handheld temperature meters can be highly accurate, achieving optimal performance requires selecting the right type of sensor, ensuring regular calibration, and considering environmental factors. Users should refer to the manufacturer's specifications for detailed accuracy information and ensure that the device is suitable for their specific application needs.