Yes, round belt pulleys can be used in high-speed applications, but several factors must be considered to ensure their effectiveness and reliability. 
Round belts, typically made from materials like polyurethane or rubber, are known for their flexibility and ability to transmit power efficiently. In high-speed applications, the choice of material is crucial as it must withstand the centrifugal forces and potential heat generated at high speeds. Polyurethane is often preferred for its durability and resistance to wear and tear.
The design of the pulley system is also critical. The pulleys must be precisely aligned to prevent slippage and ensure smooth operation. Misalignment can lead to increased wear, noise, and even belt failure. The surface finish of the pulleys should be smooth to reduce friction and wear on the belt.
Tensioning is another important aspect. Proper tension must be maintained to prevent the belt from slipping off the pulleys at high speeds. Automatic tensioners or adjustable mounts can be used to maintain the correct tension.
The diameter of the pulleys should be appropriate for the speed and load requirements. Larger diameters can help reduce the stress on the belt, but they must be balanced with the space constraints and the desired speed ratio.
Finally, environmental factors such as temperature, humidity, and exposure to chemicals should be considered, as they can affect the belt's performance and longevity. Regular maintenance and inspection are necessary to ensure the system operates efficiently and to prevent unexpected downtime.
In summary, while round belt pulleys can be used in high-speed applications, careful consideration of material, design, alignment, tensioning, and environmental factors is essential to ensure optimal performance and longevity.