The "best" adhesive for wood depends on the specific application, as different glues offer various strengths, drying times, and resistances. For general woodworking and strong, permanent bonds, PVA (Polyvinyl Acetate) wood glue, often referred to as carpenter's glue or yellow glue, is a popular choice. It's easy to use, dries relatively quickly, and creates a bond stronger than the wood itself.
For projects exposed to moisture or outdoor conditions, waterproof options like Type III PVA glues (e.g., Titebond III) or polyurethane glue are excellent. Polyurethane glue offers high strength and versatility, bonding well to a variety of materials beyond wood, but it requires moisture to cure and can expand, which might necessitate clamping.
Epoxy is ideal for filling gaps, bonding dissimilar materials, or when maximum strength and water resistance are paramount. It consists of two parts (resin and hardener) that are mixed before application, offering a strong, rigid, and waterproof bond.
Hide glue, available in liquid or granular forms, is valued by furniture restorers and musical instrument makers for its reversible nature (it can be reactivated with heat and moisture), allowing for disassembly and repair.
Ultimately, choosing the best adhesive involves considering factors such as the type of wood, environmental exposure, desired drying time, and the specific structural requirements of the project.