Yes, propylene glycol is generally considered safer than ethylene glycol. Propylene glycol is a synthetic liquid substance that absorbs water and is used in food, cosmetics, and pharmaceuticals. It is recognized as safe by the U.S. Food and Drug Administration (FDA) for use in food and cosmetics. It has a low toxicity level and is metabolized in the body to lactic acid, a normal component of the human metabolic process.
Ethylene glycol, on the other hand, is primarily used in antifreeze and industrial applications. It is highly toxic to humans and animals if ingested, inhaled, or absorbed through the skin. Ethylene glycol is metabolized in the body to glycolic acid and oxalic acid, which can cause metabolic acidosis, kidney failure, and central nervous system damage. Even small amounts can be lethal, and it requires immediate medical attention if exposure occurs.
In terms of environmental impact, propylene glycol is also considered less harmful. It is biodegradable and poses a lower risk to aquatic life compared to ethylene glycol, which can be more persistent in the environment and toxic to wildlife.
Overall, due to its lower toxicity and safer profile, propylene glycol is preferred over ethylene glycol in applications where human or animal exposure is possible, such as in food products, cosmetics, and pharmaceuticals. However, both substances should be handled with care, following appropriate safety guidelines to minimize any potential risks.